644 research outputs found
Optimisation of pipeline route in the presence of obstacles based on a least cost path algorithm and laplacian smoothing
Subsea pipeline route design is a crucial task for the offshore oil and gas industry, and the route selected can significantly affect the success or failure of an offshore project. Thus, it is essential to design pipeline routes to be eco-friendly, economical and safe. Obstacle avoidance is one of the main problems that affect pipeline route selection. In this study, we propose a technique for designing an automatic obstacle avoidance. The Laplacian smoothing algorithm was used to make automatically generated pipeline routes fairer. The algorithms were fast and the method was shown to be effective and easy to use in a simple set of case studies
Application of morphing technique with mesh-merging in rapid hull form generation
ABSTRACTMorphing is a geometric interpolation technique that is often used by the animation industry to transform one form into another seemingly seamlessly. It does this by producing a large number of ‘intermediate’ forms between the two ‘extreme’ or ‘parent’ forms. It has already been shown that morphing technique can be a powerful tool for form design and as such can be a useful addition to the armoury of product designers. Morphing procedure itself is simple and consists of straightforward linear interpolation. However, establishing the correspondence between vertices of the parent models is one of the most difficult and important tasks during a morphing process. This paper discusses the mesh-merging method employed for this process as against the already established mesh-regularising method. It has been found that the merging method minimises the need for manual manipulation, allowing automation to a large extent
End-to-End Differentiable Learning to HDR Image Synthesis for Multi-exposure Images
Recently, high dynamic range (HDR) image reconstruction based on the multiple
exposure stack from a given single exposure utilizes a deep learning framework
to generate high-quality HDR images. These conventional networks focus on the
exposure transfer task to reconstruct the multi-exposure stack. Therefore, they
often fail to fuse the multi-exposure stack into a perceptually pleasant HDR
image as the inversion artifacts occur. We tackle the problem in stack
reconstruction-based methods by proposing a novel framework with a fully
differentiable high dynamic range imaging (HDRI) process. By explicitly using
the loss, which compares the network's output with the ground truth HDR image,
our framework enables a neural network that generates the multiple exposure
stack for HDRI to train stably. In other words, our differentiable HDR
synthesis layer helps the deep neural network to train to create multi-exposure
stacks while reflecting the precise correlations between multi-exposure images
in the HDRI process. In addition, our network uses the image decomposition and
the recursive process to facilitate the exposure transfer task and to
adaptively respond to recursion frequency. The experimental results show that
the proposed network outperforms the state-of-the-art quantitative and
qualitative results in terms of both the exposure transfer tasks and the whole
HDRI process
CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1.
Calcium and integrin binding protein 1 (CIB1) is a calcium-binding protein that was initially identified as a binding partner of platelet integrin αIIb. Although CIB1 has been shown to interact with multiple proteins, its biological function in the brain remains unclear. Here, we show that CIB1 negatively regulates degeneration of dopaminergic neurons in a mouse model of Parkinson\u27s disease using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Genetic deficiency of the CIB1 gene enhances MPTP-induced neurotoxicity in dopaminergic neurons in CIB1(-/-) mice. Furthermore, RNAi-mediated depletion of CIB1 in primary dopaminergic neurons potentiated 1-methyl-4-phenyl pyrinidium (MPP(+))-induced neuronal death. CIB1 physically associated with apoptosis signal-regulating kinase 1 (ASK1) and thereby inhibited the MPP(+)-induced stimulation of the ASK1-mediated signaling cascade. These findings suggest that CIB1 plays a protective role in MPTP/MPP(+)-induced neurotoxicity by blocking ASK1-mediated signaling
Integrated In-vehicle Monitoring System Using 3D Human Pose Estimation and Seat Belt Segmentation
Recently, along with interest in autonomous vehicles, the importance of
monitoring systems for both drivers and passengers inside vehicles has been
increasing. This paper proposes a novel in-vehicle monitoring system the
combines 3D pose estimation, seat-belt segmentation, and seat-belt status
classification networks. Our system outputs various information necessary for
monitoring by accurately considering the data characteristics of the in-vehicle
environment. Specifically, the proposed 3D pose estimation directly estimates
the absolute coordinates of keypoints for a driver and passengers, and the
proposed seat-belt segmentation is implemented by applying a structure based on
the feature pyramid. In addition, we propose a classification task to
distinguish between normal and abnormal states of wearing a seat belt using
results that combine 3D pose estimation with seat-belt segmentation. These
tasks can be learned simultaneously and operate in real-time. Our method was
evaluated on a private dataset we newly created and annotated. The experimental
results show that our method has significantly high performance that can be
applied directly to real in-vehicle monitoring systems.Comment: AAAI 2022 workshop AI for Transportation accepte
Effect of rhBMP-2 applied with a 3D-printed titanium implant on new bone formation in rabbit calvarium
Objective: This study sought to compare the biocompatibility of a three-dimensional (3D)-printed titanium implant with a conventional machined titanium product, as well as the effect of such implant applied with recombinant human Bone Morphogenetic Protein Type 2 (rhBMP-2) for guided bone regeneration. Methodology: Disk-shaped titanium specimens fabricated either by the conventional machining technique or by the 3D-printing technique were compared by MC3T3-E1 cells cytotoxicity assay. New bone formation was evaluated using a rapid prototype titanium cap applied to the calvaria of 10 rabbits, which were divided into two groups: one including an atelopeptide collagen plug on one side of the cap (group I) and the other including a plug with rhBMP-2 on the other side (group II). At six and 12 weeks after euthanasia, rabbits calvaria underwent morphometric analysis through radiological and histological examination. Results: Through the cytotoxicity assay, we identified a significantly higher number of MC3T3-E1 cells in the 3D-printed specimen when compared to the machined specimen after 48 hours of culture. Moreover, morphometric analysis indicated significantly greater bone formation at week 12 on the side where rhBMP-2 was applied when evaluating the upper portion immediately below the ca p. Conclusion: The results suggest that 3D-printed titanium implant applied with rhBMP-2 enables new bone formation
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